JACKSON GABRIEL SILVER FOUNDATION AWARDS A $50,000 GRANT IN SUPPORT OF DR. JAKUB TOLAR’S RESEARCH TO TREAT AND CURE EPIDERMOLYSIS BULLOSA
The grant awarded by JGSF will support Dr. Tolar’s groundbreaking work on gene therapy, by utilizing a safer experimental technology to “fix” the genetic abnormality causing EB. The goal of Dr. Tolar’s work is to repair the cells of a child with EB, enabling those cells to produce the important missing protein Collagen VII. Once repaired, the cells would be reintroduced to the body, which would then help the skin heal. By developing these new strategies, Dr. Tolar hopes to bring the benefits of bone marrow transplants to EB patients without the traumatic and often negative consequences of such transplants.
JACKSON GABRIEL SILVER FOUNDATION AWARDS $125,000 IN GRANTS TO SUPPORT DRS. ALFRED LANE AND PETER MARINKOVICH’S RESEARCH TO TREAT EPIDERMOLYSIS BULLOSA
The JGSF grant will support Drs. Lane and Marinkovich’s protein replacement therapy, which, through a proprietary delivery method, will deliver the missing protein, type VII collagen, to the optimal location and with the optimal dose to a child suffering from EB. Replacing the missing protein in a child with Dystrophic EB would potentially enable his or her skin to act more normally, thereby changing this child’s quality of life significantly. The grant will also support the formation of the Epidermolysis Bullosa Clinical Research Consortium (EBCRC) was formed to advance knowledge about EB and to improve outcomes for affected children and adults through excellence in collaborative research, education, and advocacy. The goal is to conduct collaborative clinical and translational research in EB and improve the care of patients suffering from the disease. Current members of the EBCRC are leading physicians and researchers at the Children’s Hospital (University of Colorado), Cincinnati Children’s Hospital, Columbia University, Henry Ford Hospital (Detroit), Hospital for Sick Children (Toronto), Northwestern University, Stanford University and University of Miami. Said Dr. Lane “The EBCRC is a critical initiative in building the infrastructure to support research trials and developments in the EB community.